Chimica Generale, Eugenio Giachetti & Francesco Ranaldi, Edizioni Masterbooks
Chimica Organica e Propedeutica Biochimica, Francesco Ranaldi, Edizioni Masterbooks
Chimica generale, Peter W. Atkins & Loretta Jones, Edizioni Zanichelli
Principi di Chimica Generale e organica, E. Santaniello, M. Alberghina, M. Coletta, S. Marini, Edizioni Piccin
Stechiometria, I. Bertini, C. Luchinat, F. Mani, Casa Editrice Ambrosiana
Chimica Generale, Eugenio Giachetti & Francesco Ranaldi, Edizioni Masterbooks
Chimica Organica e Propedeutica Biochimica, Francesco Ranaldi, Edizioni Masterbooks
Chimica generale, Peter W. Atkins & Loretta Jones, Edizioni Zanichelli
Principi di Chimica Generale e organica, E. Santaniello, M. Alberghina, M. Coletta, S. Marini, Edizioni Piccin
Stechiometria, I. Bertini, C. Luchinat, F. Mani, Casa Editrice Ambrosiana
Learning Objectives - Part A
The Integrated Course provides the theoretical basis for understanding the general and organic chemistry, starting from the basic principles ( such as the structure of the atom) to the complex reactions of organic chemistry. The course also provides the methodology to solve the most common chemical exercises
The knowledge acquired allow the understanding of the structure of complex macromolecules that make up the human body and the chemical reactions of metabolism, or the topics of the Integrated Course of Biochemistry.
Learning Objectives - Part B
The Integrated Course provides the theoretical basis for understanding the general and organic chemistry, starting from the basic principles ( such as the structure of the atom) to the complex reactions of organic chemistry. The course also provides the methodology to solve the most common chemical exercises
The knowledge acquired allow the understanding of the structure of complex macromolecules that make up the human body and the chemical reactions of metabolism, or the topics of the Integrated Course of Biochemistry.
Prerequisites - Part A
Prerequisites approved by CDL
Prerequisites - Part B
Prerequisites approved by CDL
Teaching Methods - Part A
Lectures on theoretical principles and lessons provided in e-learning methodologies to solve the exercises and exercises on the same exercises
Teaching Methods - Part B
Lectures on theoretical principles and lessons provided in e-learning methodologies to solve the exercises and exercises on the same exercises
Further information - Part A
All the professors of the course receive students on request : please send an e-mail to
name.surname@unifi.it
Further information - Part B
All the professors of the course receive students on request : please send an e-mail to
name.surname@unifi.it
Type of Assessment - Part A
Both written and oral examination on the whole program, to be faced together in the same exam session at the end of the course
Type of Assessment - Part B
Both written and oral examination on the whole program, to be faced together in the same exam session at the end of the course
Course program - Part A
- Composition of the atom; isotopes and atomic weight; force that holds together the protons in the nucleus and the mass defect; The concept of mole.
- Wave equation and wave functions; atomic orbitals.
- Electronic configuration of the elements by the rules of AUFBAU, electronic configuration; organizational criteria of the elements and performance of periodic properties of the elements.
- Ionization energy, electron affinity, electronegativity; octet rule; ionic and covalent chemical bond.
- Ionic compounds and lattice energy associated with them
- Properties of the covalent bond; covalent bonds homopolar and heteropolar, single, double and triple, conventional or dative, sigma and π.
- Hybridization of atomic orbitals; VSEPR principle and concept of resonance; structural formulas and brute formula of a compound; classes of inorganic chemical compounds.
- van der Waals forces and hydrogen bond; states of matter, relationship between cohesion forces, kinetic energy and state of aggregation; main types of compounds.
- Gas state; gas laws; state diagrams.
- Solution and solvation; concentration of a solution; osmotic pressure; homogeneous mixtures, heterogeneous and colloidal.
- Chemical reactions; oxidation state and redox reactions.
- Thermodynamics of reactions; enthalpy, entropy and free energy in the reactions; the general principles of thermochemical and Hess law.
- Reaction rate; chemical, kinetic constant speed, reaction order, factors that affect the rate of reaction; models describing the reaction mechanisms; catalysis.
- Law of mass action; relationship between ΔG ° and the equilibrium constant; the degree of dissociation; Le Chatelier's principle.
- Auto ionization of water; pH and pOH; main acid-base theories; weak and strong acids and bases; acid-base balance in solution; acids and mono- and multi-functional bases, amphoteric substances and salts with acid-base properties; buffer solutions, acid-base titrations.
- Electrochemical Basics; main types of batteries, with particular reference to the batteries used in the medical field.
- Carbon compounds and molecular formulas, and rational structure.
- IUPAC nomenclature; chemical and physical properties and characteristics of reactions and synthesis of the main classes of organic compounds.
- Meaning and biological reflexes of stereoisomery phenomenon of organic molecules.
- Aliphatic and aromatic hydrocarbons.
- Acyl halides
- Alcohols, ethers, polyhydric alcohols, phenols and thiols of biological interest.
- Aldehydes and ketones.
- Carboxylic acids, dicarboxylic acids, hydroxy acids and keto acids of biochemical interest; functional derivatives of carboxylic acids (acyl chlorides, esters, amides and anhydrides).
- Aliphatic and aromatic amines.
- Carbohydrates (monosaccharides, with particular emphasis on their stereochemistry), disaccharides and polysaccharides; lipids (triglycerides, phospholipids and steroid hormones);
- Amino acids, with particular reference to the peptide bond.
- main aromatic heterocyclic structures and not, with reference to the compounds of biochemical interest.
Course program - Part B
- Composition of the atom; isotopes and atomic weight; force that holds together the protons in the nucleus and the mass defect; The concept of mole.
- Wave equation and wave functions; atomic orbitals.
- Electronic configuration of the elements by the rules of AUFBAU, electronic configuration; organizational criteria of the elements and performance of periodic properties of the elements.
- Ionization energy, electron affinity, electronegativity; octet rule; ionic and covalent chemical bond.
- Ionic compounds and lattice energy associated with them
- Properties of the covalent bond; covalent bonds homopolar and heteropolar, single, double and triple, conventional or dative, sigma and π.
- Hybridization of atomic orbitals; VSEPR principle and concept of resonance; structural formulas and brute formula of a compound; classes of inorganic chemical compounds.
- van der Waals forces and hydrogen bond; states of matter, relationship between cohesion forces, kinetic energy and state of aggregation; main types of compounds.
- Gas state; gas laws; state diagrams.
- Solution and solvation; concentration of a solution; osmotic pressure; homogeneous mixtures, heterogeneous and colloidal.
- Chemical reactions; oxidation state and redox reactions.
- Thermodynamics of reactions; enthalpy, entropy and free energy in the reactions; the general principles of thermochemical and Hess law.
- Reaction rate; chemical, kinetic constant speed, reaction order, factors that affect the rate of reaction; models describing the reaction mechanisms; catalysis.
- Law of mass action; relationship between ΔG ° and the equilibrium constant; the degree of dissociation; Le Chatelier's principle.
- Auto ionization of water; pH and pOH; main acid-base theories; weak and strong acids and bases; acid-base balance in solution; acids and mono- and multi-functional bases, amphoteric substances and salts with acid-base properties; buffer solutions, acid-base titrations.
- Electrochemical Basics; main types of batteries, with particular reference to the batteries used in the medical field.
- Carbon compounds and molecular formulas, and rational structure.
- IUPAC nomenclature; chemical and physical properties and characteristics of reactions and synthesis of the main classes of organic compounds.
- Meaning and biological reflexes of stereoisomery phenomenon of organic molecules.
- Aliphatic and aromatic hydrocarbons.
- Acyl halides
- Alcohols, ethers, polyhydric alcohols, phenols and thiols of biological interest.
- Aldehydes and ketones.
- Carboxylic acids, dicarboxylic acids, hydroxy acids and keto acids of biochemical interest; functional derivatives of carboxylic acids (acyl chlorides, esters, amides and anhydrides).
- Aliphatic and aromatic amines.
- Carbohydrates (monosaccharides, with particular emphasis on their stereochemistry), disaccharides and polysaccharides; lipids (triglycerides, phospholipids and steroid hormones);
- Amino acids, with particular reference to the peptide bond.
- main aromatic heterocyclic structures and not, with reference to the compounds of biochemical interest.